토끼의 하악골체부에 식립된 임플란트 주위에서 Beta-tricalciumphosphate 골이식재의 골형성효과에 대한 조직계측학적 연구
Histomorphometric Analysis on Bone Formation Effect of Beta-tricalciumphosphate around Dental Implants in Rabbit Mandibular Body: Pilot Study
편영훈, 김일규, 조현영, 주상현, 정범상, 배상필, 조현우,
소속 상세정보
편영훈 ( Pyun Young-Hoon ) - 인하대학교 의과대학 치과학교실 구강악안면외과
김일규 ( Kim Ill-Kyu ) - 인하대학교 의과대학 치과학교실 구강악안면외과
조현영 ( Cho Hyun-Young ) - 인하대학교 의과대학 치과학교실 구강악안면외과
주상현 ( Ju Sang-Hyun ) - 인하대학교 의과대학 치과학교실 구강악안면외과
정범상 ( Jung Bum-Sang ) - 인하대학교 의과대학 치과학교실 구강악안면외과
배상필 ( Pae Sang-Pill ) - 인하대학교 의과대학 치과학교실 구강악안면외과
조현우 ( Cho Hyun-Woo ) - 인하대학교 의과대학 치과학교실 구강악안면외과
KMID : 1036320130350050294
Abstract
Purpose: The purpose of this study is to assess the effectiveness of beta-tricalciumphosphate (-TCP) as a bone graft material on new bone formation and regeneration of mandible bone defect around dental implants.
Methods: Both mandibular sites of ten rabbits were exposed. The experimental subjects were divided into two groups. Rabbits in the control group (right site of the mandible) had dental implants around cortical bone defects, without treatment, while, in the experimental group (left site of the mandible), -TCP was grafted into the bone defect around the implant. Rabbits were sacrificed after one, two, three, four, and eight weeks, and histomorphometric evaluation and analysis of the bone implant contact rate were performed using an optical microscope.
Results: Bone formation rates in the experimental group were greater than those in the control group from one to eight weeks, and percentages of implant surface contacted to bone were greater in the experimental group than in the control group from three weeks after implantation.
Conclusion: These results suggest that the bone formation activity around dental implants was increased by osteoconduction activity of -TCP.
키워드
Implant;Beta-tricalcium phosphate;Osteoconduction
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